Cephalexin

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What they say about it
Starting with a penicillin-producing microbial strain, DSM introduced and optimized two enzyme-encoding genes for a one-step direct fermentation of adipoyl-7-ADCA, which could then be converted into Cephalexin via two enzymatic steps. The new process replaced a 13-step chemical process, resulting in significant cost and energy savings.
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How they say it works
DSM’s Green Technology uses biocatalyses to produce active Health & Medicine ingredients for antibiotics, including Cephalexin. Rather than a 13-step fermentation process, the company has developed a process with “two enzymatic steps” that use metabolic engineering to produce the ingredients, which reduces emissions, resource and energy consumption, toxicity and risk potential, and area use when compared with the older process.
Market Status
Synbio Components
Websites
www.dsm.com