http://synbioproject.tech/cpi/applications/succinic-acid/
Succinic acid is a dicarboxylic acid used in food and beverages as a sweetener, among other uses, which has traditionally been produced from petroleum-based feedstocks. In addition to food uses, succinic acid is used in drugs, cosmetics, and the production process for numerous chemicals and polymers.
BioAmber has developed a process to produce succinic acid via bacterial fermentation of glucose, rather than using petroleum-based feedstocks. According to the Environmental Protection Agency (EPA), which awarded BioAmber a “green chemistry” award in 2011, the company “has successfully scaled up an E. coli biocatalyst licensed from the Department of Energy and integrated a novel, water-based downstream purification process,” which forms the basis for the fermentation process.